De Soto Animal Health Biologics Manufacturing Expansion

Merck Animal Health's 200,000 sq ft expansion of its existing biologics manufacturing site in De Soto, Kansas adds filling and freeze-dryer capacity for large-molecule animal vaccines and biologic products, designated a Center of Excellence within Merck's animal health network. The May 8, 2025 announcement totalled $895 million and itemized it cleanly as $860 million for the manufacturing facility and $35 million for research and development laboratories; AFT records only the $860 million manufacturing component. Merck said the project will create more than 200 full-time roles, recorded here at that conservative floor, with commercial manufacturing expected to begin in 2030 at year precision. Site preparation and facility design began immediately, but no groundbreaking has been confirmed, so the record remains in Planning. The $35 million research component, 2,500 construction jobs, the site's retained existing workforce, and Merck's national investment rollups are excluded.

Investment
$860.0M
Permanent jobs announced
more than200
Status
Planning
Expected opening
2030
Why this project qualifies

With $860 million in facility-specific investment and more than 200 permanent operating jobs announced, this project clears both of AFT's qualifying thresholds ($100 million in facility-specific investment OR 100 permanent operating jobs). It is also confirmed by official public sources and involves a physical manufacturing facility in the United States.

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Why it matters

The pharmaceuticals context.

Pharmaceutical manufacturers are committing billions to new U.S. production capacity for active ingredients, injectable medicines, biologics and other high-demand treatments. North Carolina and Indiana remain major centers of investment, while new facilities are being planned across the South. The current project pipeline includes both large greenfield campuses and major expansions of established production sites.

Project record

At a glance

Company
Merck (Animal Health)
Industry
Pharmaceuticals
Location
De Soto, Kansas
Investment
$860.0M
Permanent jobs announced
More than 200
Status
Planning
Announced
May 8, 2025
Expected opening
2030
Added to tracker
Sep 1, 2026
Sources

Official references

Cite this project

American Factory Tracker. "De Soto Animal Health Biologics Manufacturing Expansion — Merck, De Soto, KS." https://americanfactorytracker.com/projects/merck-animal-health-de-soto-manufacturing-expansion. Accessed November 4, 2026.

Please also cite the original sources listed above for underlying figures.

Back to the tracker/projects/merck-animal-health-de-soto-manufacturing-expansion

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