With 200 permanent operating jobs announced, this project clears AFT's 100-permanent-job threshold (AFT includes any project meeting $100 million in facility-specific investment OR 100 permanent operating jobs). It is also confirmed by official public sources and involves a physical manufacturing facility in the United States.
View full methodology →The pharmaceuticals context.
Pharmaceutical manufacturers are committing billions to new U.S. production capacity for active ingredients, injectable medicines, biologics and other high-demand treatments. North Carolina and Indiana remain major centers of investment, while new facilities are being planned across the South. The current project pipeline includes both large greenfield campuses and major expansions of established production sites.
At a glance
- Company
- AstraZeneca
- Industry
- Pharmaceuticals
- Location
- Frederick, Maryland
- Investment
- Not disclosed
- Permanent jobs announced
- 200
- Status
- Planning
- Announced
- Nov 21, 2025
- Expected opening
- 2029
- Added to tracker
- Sep 1, 2026
Official references
- AstraZeneca's November 21, 2025 $2 billion Maryland manufacturing announcement (Frederick + Gaithersburg) https://www.astrazeneca.com/media-centre/press-releases/2025/astrazeneca-plans-dollar2-billion-manufacturing-investment-in-maryland-supporting-2600-jobs-and-catalysing-economic-growth.html
- Maryland Governor's Office announcement of the $2 billion AstraZeneca investment https://governor.maryland.gov/news/press-releases/governor-moore-and-astrazeneca-announce-2-billion-investment-expand-manufacturing-maryland
Cite this project
American Factory Tracker. "Frederick Biologics Manufacturing Expansion — AstraZeneca, Frederick, MD." https://americanfactorytracker.com/projects/astrazeneca-frederick-biologics-expansion. Accessed November 4, 2026.
Please also cite the original sources listed above for underlying figures.